Actors:
- Michael Gross (Steven Keaton)
- Michael J. Fox (Alex P. Keaton)
- Justine Bateman (Mallory Keaton)
- Tina Yothers (Jennifer Keaton)
- Meredith Baxter (Elyse Keaton)
- Brian Bonsall (Andrew 'Andy' Keaton)
- Marc Price (Irwin 'Skippy' Handelman)
- Scott Valentine (Nick Moore)
- Courteney Cox (Lauren Miller (21 episodes, 1987-1989))
- Tracy Pollan (Ellen Reed (13 episodes, 1985-1987))
- John Hancock (Gus Thompson (7 episodes, 1983-1989))
- Robert Schanche (Sam / ... (6 episodes, 1983-1989))
- Enid Kent (Phyllis / ... (6 episodes...)
- Terry Wills (Dr. Schulte)
- Alan Blumenfeld (George Bellack)
- Alan Blumenfeld (George Bellack)
- Norman Parker (Robert Keaton)
- Robert Costanzo (Carmine / ... (5 episodes...)
- John Petlock (Ted Waterman)
- David Wohl (Psychiatrist / ... (5 episodes...)
- John Dukakis (Jeff Wakefield (4 episodes, 1983-1984))
- Ben Piazza (Mr. Wertz / ... (4 episodes...)
- Michael David Wright (Young Steven)
- Tom Hanks (Ned Donnelly)
- Bunny Summers (Customer #1 / ... (3 episodes...)
- John Putch (Neil / ... (3 episodes, 1982-1986))
- Belita Moreno (Bernice / ... (3 episodes...)
- Timothy Busfield (Doug)
- Denise D'Amico (Customer #2 / ... (3 episodes...)
- Walter Olkewicz (Bill Channing / ... (3 episodes...)
- James N. Hamilton (Bellhop / ... (3 episodes...)
- Matthew Faison (Dr. Skip Williamson / ... (3...)
- Michael B. Moynahan (Grover Garver / ... (3 episodes...)
- Margaret Marx (Young Elyse (3 episodes, 1986-1988))
- Raymond Singer (Buffaloed Bill / ... (3...)
- Melinda Culea (Rebecca Ryan (3 episodes, 1986-1987))
- Jane Adams (Marty Brodie / ... (3 episodes...)
- Richard McGonagle (Brother Timothy / ... (3...)
- Philip Baker Hall (Dr. Harrison)
- Anne Seymour (May Keaton (2 episodes, 1985))
- Priscilla Morrill (Kate / ... (2 episodes, 1982-1984))
- Sal Viscuso (Richard Grasso / ... (2...)
- Mary Farrell (Carol Mannings / ... (2...)
- Richard Venture (Mr. Carlyle (2 episodes, 1983))
- Adam Carl (Young Steven Keaton)
- Philip Sterling (Mr. Winkler (2 episodes, 1982-1984))
- Brooke Alderson (Suzanne Davis (2 episodes, 1982-1983))
- Jay Tarses (Ron Davis)
- Sam Whipple (Bill / ... (2 episodes, 1984))
- Daphne Zuniga (Rachel Miller (2 episodes, 1984))
- Rick Podell (Jackie Jackerman (2 episodes, 1985))
- Suzanne Snyder (Tricia Armstrong (2 episodes, 1985))
- Jeffrey Joseph (James Jarrett (2 episodes, 1984-1985))
- Earl Boen (Attendant / ... (2 episodes...)
- Geena Davis (Karen Nicholson (2 episodes, 1984))
- Jack Blessing (Leonard)
- David Paymer (Larry Harris)
- Chris Hebert (Young Alex (2 episodes, 1982-1983))
- Michael Alldredge (Young Jake Keaton)
- Karlene Crockett (Marge (2 episodes, 1985))
- Julie Fulton (Suzie Harris (2 episodes, 1985))
- Maryedith Burrell (Young May (2 episodes, 1985))
- Mark Marias (Young Robert Keaton)
- Ron Karabatsos (Bud Carlson (2 episodes, 1985))
- Hanna Hertelendy (Mrs. Kretzer (2 episodes, 1985))
- Wiley Harker (Mr. Kretzer (2 episodes, 1985))
- Robert Martin Steinberg (Neighbor (2 episodes, 1985))
- Barbara Minkus (Neighbor (2 episodes, 1985))
- Edward Edwards (Mr. Rubin Tedesco / ... (2...)
- Lois De Banzie (Mrs. Rose Handleman / ... (2...)
- Michael Zorek (Flaum (2 episodes, 1984-1986))
- Tracy Nelson (Deena / ... (2 episodes, 1984-1985))
- Dan Hedaya (Joe Moore)
- Joseph Gordon-Levitt (Dougie)
- Raleigh Bond (Harry Handleman / ... (2...)
- John Hostetter (Anchorman / ... (2 episodes...)
- Bernadette Birkett (Carol / ... (2 episodes, 1985-1988))
- Jeff Cohen (Dougie Barker / ... (2 episodes...)
- Ford Austin (Todd (2 episodes, 1984-1985))
- Marc Wasserman (Ted (2 episodes, 1984-1985))
- Garrett Merriman (Baby Andrew 'Andy' Keaton)
- Taylor Merriman (Baby Andrew 'Andy' Keaton)
- Anne Bellamy (Boardwoman / ... (2 episodes...)
- Jason Naylor (Simon Wickerson)
- Julie Cobb (Maureen Keaton (2 episodes, 1987))
- Alyson Croft (Brooke (2 episodes, 1987))
- Sonia Curtis (Amy Sussman (2 episodes, 1987))
- Gino De Mauro (Zack (2 episodes, 1987))
- Stephanie Dizon (Holly (2 episodes, 1987))
- Niall Gartlan (Brett (2 episodes, 1987))
- Heather Hobbs (Stacie Connors (2 episodes, 1987))
- Tammy Lauren (Marilyn Keaton (2 episodes, 1987))
- Amy Lynne (Chrissy Nardino (2 episodes, 1987))
- Brian McNamara (Greg)
- Wendel Meldrum (Kathy Brady (2 episodes, 1987))
- Nicole Nourmand (Beth (2 episodes, 1987))
- Fess Reynolds (Reggie (2 episodes, 1987))
- Blake Soper (Jonathan Keaton (2 episodes, 1987))
- Wendy Wells-Gunkel (Cheering Student / ... (2...)
- Meg Wyllie (Mrs. Leahy (2 episodes, 1987))
- Kevin Dunn (Bob / ... (2 episodes, 1988-1989))
- Baillie Gerstein (Mrs. Hummier / ... (2 episodes...)
- Billy Morrissette (Paul Corman / ... (2 episodes...)
- Bibi Besch (Dr. Hewitt (2 episodes, 1988))
- Christian Clemenson (Mr. Flaherty)
- Richard Kuss (Mr. Meyers (2 episodes, 1988))
- Caroline Mignini (Peggy Vincent (2 episodes, 1988))
- Christina Pickles (Ruth Hobart (2 episodes, 1988))
- Keith Amos (Michael Thompson (2 episodes, 1989))
- Rosalind Cash (Maya Thompson (2 episodes, 1989))
- Mark L. Taylor (Phil)
- Michael Gross (Steven Keaton)
- Michael J. Fox (Alex P. Keaton)
- Justine Bateman (Mallory Keaton)
- Tina Yothers (Jennifer Keaton)
- Meredith Baxter (Elyse Keaton)
- Brian Bonsall (Andrew 'Andy' Keaton)
- Marc Price (Irwin 'Skippy' Handelman)
- Scott Valentine (Nick Moore)
- Courteney Cox (Lauren Miller (21 episodes, 1987-1989))
- Tracy Pollan (Ellen Reed (13 episodes, 1985-1987))
- John Hancock (Gus Thompson (7 episodes, 1983-1989))
- Robert Schanche (Sam / ... (6 episodes, 1983-1989))
- Enid Kent (Phyllis / ... (6 episodes...)
- Terry Wills (Dr. Schulte)
- Alan Blumenfeld (George Bellack)
- Norman Parker (Robert Keaton)
- Robert Costanzo (Carmine / ... (5 episodes...)
- John Petlock (Ted Waterman)
- David Wohl (Psychiatrist / ... (5 episodes...)
- John Dukakis (Jeff Wakefield (4 episodes, 1983-1984))
- Ben Piazza (Mr. Wertz / ... (4 episodes...)
- Michael David Wright (Young Steven)
- Tom Hanks (Ned Donnelly)
- Bunny Summers (Customer #1 / ... (3 episodes...)
- John Putch (Neil / ... (3 episodes, 1982-1986))
- Belita Moreno (Bernice / ... (3 episodes...)
- Timothy Busfield (Doug)
- Denise D'Amico (Customer #2 / ... (3 episodes...)
- Walter Olkewicz (Bill Channing / ... (3 episodes...)
- James N. Hamilton (Bellhop / ... (3 episodes...)
- Matthew Faison (Dr. Skip Williamson / ... (3...)
- Michael B. Moynahan (Grover Garver / ... (3 episodes...)
- Margaret Marx (Young Elyse (3 episodes, 1986-1988))
- Raymond Singer (Buffaloed Bill / ... (3...)
- Melinda Culea (Rebecca Ryan (3 episodes, 1986-1987))
- Jane Adams (Marty Brodie / ... (3 episodes...)
- Richard McGonagle (Brother Timothy / ... (3...)
- Philip Baker Hall (Dr. Harrison)
- Anne Seymour (May Keaton (2 episodes, 1985))
- Priscilla Morrill (Kate / ... (2 episodes, 1982-1984))
- Sal Viscuso (Richard Grasso / ... (2...)
- Mary Farrell (Carol Mannings / ... (2...)
- Richard Venture (Mr. Carlyle (2 episodes, 1983))
- Adam Carl (Young Steven Keaton)
- Philip Sterling (Mr. Winkler (2 episodes, 1982-1984))
- Brooke Alderson (Suzanne Davis (2 episodes, 1982-1983))
- Jay Tarses (Ron Davis)
- Sam Whipple (Bill / ... (2 episodes, 1984))
- Daphne Zuniga (Rachel Miller (2 episodes, 1984))
- Rick Podell (Jackie Jackerman (2 episodes, 1985))
- Suzanne Snyder (Tricia Armstrong (2 episodes, 1985))
- Jeffrey Joseph (James Jarrett (2 episodes, 1984-1985))
- Earl Boen (Attendant / ... (2 episodes...)
- Geena Davis (Karen Nicholson (2 episodes, 1984))
- Jack Blessing (Leonard)
- David Paymer (Larry Harris)
- Chris Hebert (Young Alex (2 episodes, 1982-1983))
- Michael Alldredge (Young Jake Keaton)
- Karlene Crockett (Marge (2 episodes, 1985))
- Julie Fulton (Suzie Harris (2 episodes, 1985))
- Maryedith Burrell (Young May (2 episodes, 1985))
- Mark Marias (Young Robert Keaton)
- Ron Karabatsos (Bud Carlson (2 episodes, 1985))
- Hanna Hertelendy (Mrs. Kretzer (2 episodes, 1985))
- Wiley Harker (Mr. Kretzer (2 episodes, 1985))
- Robert Martin Steinberg (Neighbor (2 episodes, 1985))
- Barbara Minkus (Neighbor (2 episodes, 1985))
- Edward Edwards (Mr. Rubin Tedesco / ... (2...)
- Lois De Banzie (Mrs. Rose Handleman / ... (2...)
- Michael Zorek (Flaum (2 episodes, 1984-1986))
- Tracy Nelson (Deena / ... (2 episodes, 1984-1985))
- Dan Hedaya (Joe Moore)
- Joseph Gordon-Levitt (Dougie)
- Raleigh Bond (Harry Handleman / ... (2...)
- John Hostetter (Anchorman / ... (2 episodes...)
- Bernadette Birkett (Carol / ... (2 episodes, 1985-1988))
- Jeff Cohen (Dougie Barker / ... (2 episodes...)
- Ford Austin (Todd (2 episodes, 1984-1985))
- Marc Wasserman (Ted (2 episodes, 1984-1985))
- Garrett Merriman (Baby Andrew 'Andy' Keaton)
- Taylor Merriman (Baby Andrew 'Andy' Keaton)
- Anne Bellamy (Boardwoman / ... (2 episodes...)
- Jason Naylor (Simon Wickerson)
- Julie Cobb (Maureen Keaton (2 episodes, 1987))
- Alyson Croft (Brooke (2 episodes, 1987))
- Sonia Curtis (Amy Sussman (2 episodes, 1987))
- Gino De Mauro (Zack (2 episodes, 1987))
- Stephanie Dizon (Holly (2 episodes, 1987))
- Niall Gartlan (Brett (2 episodes, 1987))
- Heather Hobbs (Stacie Connors (2 episodes, 1987))
- Tammy Lauren (Marilyn Keaton (2 episodes, 1987))
- Amy Lynne (Chrissy Nardino (2 episodes, 1987))
- Brian McNamara (Greg)
- Wendel Meldrum (Kathy Brady (2 episodes, 1987))
- Nicole Nourmand (Beth (2 episodes, 1987))
- Fess Reynolds (Reggie (2 episodes, 1987))
- Blake Soper (Jonathan Keaton (2 episodes, 1987))
- Wendy Wells-Gunkel (Cheering Student / ... (2...)
- Meg Wyllie (Mrs. Leahy (2 episodes, 1987))
- Kevin Dunn (Bob / ... (2 episodes, 1988-1989))
- Baillie Gerstein (Mrs. Hummier / ... (2 episodes...)
- Billy Morrissette (Paul Corman / ... (2 episodes...)
- Bibi Besch (Dr. Hewitt (2 episodes, 1988))
- Christian Clemenson (Mr. Flaherty)
- Richard Kuss (Mr. Meyers (2 episodes, 1988))
- Caroline Mignini (Peggy Vincent (2 episodes, 1988))
- Christina Pickles (Ruth Hobart (2 episodes, 1988))
- Keith Amos (Michael Thompson (2 episodes, 1989))
- Rosalind Cash (Maya Thompson (2 episodes, 1989))
- Mark L. Taylor (Phil)
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